发明名称 INDOLE DERIVATIVE
摘要 <p>There is provided an indole derivative represented by the above formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of malignant tumor or a brain neurodegenerative disease: &lt;CHEM&gt; (wherein C ring represents a benzene ring or a cyclohexene ring; X and Y are the same or different and each represent -CH2-, -CH(OH)-, -CH(OR&lt;X&gt;)-, -CH(SR&lt;Y&gt;)- or carbonyl; R&lt;1&gt; and R&lt;2&gt; are the same ordifferent and each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or substituted or unsubstituted lower alkanoyl or R&lt;1&gt; and R&lt;2&gt; form a benzene ring together two carbon atoms each being adjacent thereto; and R&lt;3&gt;, R&lt;4&gt; and R&lt;5&gt; are the same or different and each represent a hydrogen atom, substituted or unsubstituted lower alkyl, etc.)</p>
申请公布号 EP1464645(A1) 申请公布日期 2004.10.06
申请号 EP20020788851 申请日期 2002.12.17
申请人 KYOWA HAKKO KOGYO CO., LTD. 发明人 KANAI, FUMIHIKO;MURAKATA, CHIKARA;TSUJITA, TETSUYA;YAMASHITA, Y.;MIZUKAMI, TAMIO;AKINAGA, SHIRO
分类号 A61K31/407;A61K31/409;A61K31/4196;A61K31/422;A61K31/4439;A61K31/497;A61K31/5377;A61K31/541;A61P25/00;A61P35/00;A61P43/00;C07D403/04;C07D487/04;C07D487/22;(IPC1-7):C07D487/04;A61K31/537;A61K31/419;A61K31/443 主分类号 A61K31/407
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