发明名称 |
INDOLE DERIVATIVE |
摘要 |
<p>There is provided an indole derivative represented by the above formula (I) or a pharmaceutically acceptable salt thereof which is useful for the treatment of malignant tumor or a brain neurodegenerative disease: <CHEM> (wherein C ring represents a benzene ring or a cyclohexene ring; X and Y are the same or different and each represent -CH2-, -CH(OH)-, -CH(OR<X>)-, -CH(SR<Y>)- or carbonyl; R<1> and R<2> are the same ordifferent and each represent a hydrogen atom, substituted or unsubstituted lower alkyl, substituted or unsubstituted lower alkenyl or substituted or unsubstituted lower alkanoyl or R<1> and R<2> form a benzene ring together two carbon atoms each being adjacent thereto; and R<3>, R<4> and R<5> are the same or different and each represent a hydrogen atom, substituted or unsubstituted lower alkyl, etc.)</p> |
申请公布号 |
EP1464645(A1) |
申请公布日期 |
2004.10.06 |
申请号 |
EP20020788851 |
申请日期 |
2002.12.17 |
申请人 |
KYOWA HAKKO KOGYO CO., LTD. |
发明人 |
KANAI, FUMIHIKO;MURAKATA, CHIKARA;TSUJITA, TETSUYA;YAMASHITA, Y.;MIZUKAMI, TAMIO;AKINAGA, SHIRO |
分类号 |
A61K31/407;A61K31/409;A61K31/4196;A61K31/422;A61K31/4439;A61K31/497;A61K31/5377;A61K31/541;A61P25/00;A61P35/00;A61P43/00;C07D403/04;C07D487/04;C07D487/22;(IPC1-7):C07D487/04;A61K31/537;A61K31/419;A61K31/443 |
主分类号 |
A61K31/407 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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