| 发明名称 |
Benzopyranverbindingen voor gebruik bij de behandeling en preventie van ontstekingsgerelateerde aandoeningen. |
| 摘要 |
The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula 1 Wherein Z, X, R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, and R<SUP>4 </SUP>are as described in the specification. |
| 申请公布号 |
NL1025844(A1) |
申请公布日期 |
2004.10.01 |
| 申请号 |
NL20041025844 |
申请日期 |
2004.03.29 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
KARL WILLIAM ASTON;DAVID LOUIS BROWN;JEFFREY STEVEN CARTER;ANGELA M. DEPROW;THERESA R. FLETCHER;E. ANN HALLINAN;BRUCE CAMERON HAMPER;RENEE M. HUFF;JAMES RICHARD KIEFER JR.;FRANCIS KOSZYK;STEVEN W. KRAMER;SUBO LIAO;DAVID CHRISTOPHER LIMBURG;JOHN ROBERT SPRINGER;SOFYA TSYMBALOV;LIJUAN JANE WANG;LI XING;YI YU |
| 分类号 |
A61K31/353;A61K31/382;A61K31/47;A61P29/00;C07D215/54;C07D311/58;C07D311/64;C07D311/94;C07D405/04;C07D405/06;C07D405/12;C07D407/04;C07D407/12;C07D409/04;C07D409/06;C07D409/12;C07D409/14;C07D417/06;C07D493/04 |
主分类号 |
A61K31/353 |
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