| 摘要 |
PROBLEM TO BE SOLVED: To provide a sustained release type compounded unit preparation, while keeping the strength sufficiently in digestive tract, also setting the degree of release of an active ingredient into the body in a suitable state, and surely capable of exhibiting the effect by the active ingredient in the unit preparation. SOLUTION: This sustained release type compounded unit preparation is provided by blending a unit-forming substance with 5-ä2-[2-(O-ethoxyphenoxy)ethylamino]propyl}-2-methoxybenzenesulfonamide hydrochloride, further adding a dissolution-regulating agent and granulating. The unit-forming substance consists mainly of lactose and crystalline cellulose and further the blending ratio of the lactose to crystalline cellulose is made within (50:59)-(45:55) range in weight ratio. COPYRIGHT: (C)2004,JPO&NCIPI
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