Restricted access material for spme

摘要

This invention relates to a stationary phase for solid phase microextraction (SPME) comprising a surface built up by a RAM (restricted access material) phase, a device for SPME comprising said stationary phase and a method for SPME using said stationary phase. The RAM SPME stationary phases according to the invention are robust, providing many direct extractions and subsequent determinations, while overcoming the present disadvantages of direct sampling of biological matrices by SPME.