COMBINED USE OF G-CSF AND FACTORS HAVING ANGIOGENIC ACTION

摘要

A remedy efficacious against ischemic diseases which contains, as the active ingredients, granulocyte colony stimulating factor (G-CSF), and hepatocyte growth factor (HGF) or fibroblast growth factor (FGF). Administration of thi s remedy provides an efficacious therapy of overcoming the faults observed particularly in the existing exercise therapy, drug therapy and revascularization for obstructive arteriosclerosis and gene therapy and intramuscular transplantation of bone marrow cells proposed recently. Moreover, this remedy is also usable as a remedy for ischemic diseases such as ischemic cerebrovascular injury and ischemic heart diseases.