发明名称 |
Methods of enhancing radiation effects with metal nanoparticles |
摘要 |
The present invention provides methods of using metal nanoparticles 0.5 to 400 nm in diameter to enhance the dose and effectiveness of x-rays or of other kinds of radiation in therapeutic regimes of ablating a target tissue such as tumor. The metal nanoparticles can be administered intravenously, intra-arterially, or locally to achieve specific loading in and around the target tissue. The metal nanoparticles can also be linked to chemical and/or biochemical moieties which bind specifically to the target tissue. The enhanced radiation methods can also be applied to ablate unwanted tissues or cells ex vivo.
|
申请公布号 |
US2004181114(A1) |
申请公布日期 |
2004.09.16 |
申请号 |
US20030387059 |
申请日期 |
2003.03.12 |
申请人 |
HAINFELD JAMES F.;SLATKIN DANIEL N. |
发明人 |
HAINFELD JAMES F.;SLATKIN DANIEL N. |
分类号 |
A61B6/00;A61K41/00;A61K47/48;A61K49/22;A61N1/40;A61N5/00;A61N5/06;A61N5/10;(IPC1-7):A61N5/00 |
主分类号 |
A61B6/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|