| 发明名称 |
Methods of determining precise HERG interactions and designing compounds based on said interactions |
| 摘要 |
The present invention discloses methods of determining highly precise interactions between the HERG ion channel and various compounds. The methods of the present invention utilize the nonsense codon suppression methods combined with heterologous in vivo expression in Xenopus oocytes.
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| 申请公布号 |
US2004180401(A1) |
申请公布日期 |
2004.09.16 |
| 申请号 |
US20030444058 |
申请日期 |
2003.05.23 |
| 申请人 |
NEURION PHARMACEUTICALS, INC. |
发明人 |
DOUGHERTY DENNIS A.;LESTER HENRY A.;LASCH JONATHAN G. |
| 分类号 |
C07H21/04;C07K1/107;C07K14/705;C12P21/02;C12Q;C12Q1/00;C12Q1/68;G01N33/53;G01N33/566;G01N33/68;(IPC1-7):C12Q1/68 |
主分类号 |
C07H21/04 |
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