USE OF CC-CHEMOKINE MUTANTS AGAINST LIVER DISEASES
摘要
CC-chemokine mutants having reduced Glycosaminoglycans (GAG)-binding properties are effective against liver fibrotic inflammatory and/or autoimmune diseases. Particularly preferred are the mutants of CCL5/RANTES having reduced GAG-binding properties.
申请公布号
WO2004062688(A3)
申请公布日期
2004.09.16
申请号
WO2003EP51090
申请日期
2003.12.22
申请人
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.;PROUDFOOT, AMANDA;AJUEBOR, MAUREEN;SWAIN, MARK