摘要 |
<p>The present invention relates to a process for animal, preferably human, diploid anchorage-dependent cell culture, in the absence of exogenous components of primary animal origin, and to a cell culture medium substantially free of exogenous components of primary animal origin suitable for carrying out said process. In particular the invention concerns a cell culture medium which comprises at least one, more preferably several, exogenous animal-free growth factors. The present invention also relates to a process for cultivating animal, preferably human diploid anchorage-dependent cells in a medium according to the invention, involving the use of a trypsin substitute of non-animal origin for passaging cells. The invention further relates to a process for producing viruses, viral vaccines and the like.</p> |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A.;AERTS, BRIGITTE, GHISLAINE, LOUISE;GHISLAIN, YVES, JULES, MAURICE;GONZE, MARIE-MONIQUE, JANE;KNOTT, ISABELLE, SOLANGE, LUCIE;MAGGETTO, CARINE |
发明人 |
AERTS, BRIGITTE, GHISLAINE, LOUISE;GHISLAIN, YVES, JULES, MAURICE;GONZE, MARIE-MONIQUE, JANE;KNOTT, ISABELLE, SOLANGE, LUCIE;MAGGETTO, CARINE |