发明名称 BENZOFURAN DERIVATIVE
摘要 A compound represented by the general formula (1): (wherein R1 represents optionally substituted alkyl or optionally substituted alkenyl; and R2 and R 3 each represents hydrogen, alkyl, hydroxyalkyl, dihydroxyalkyl, or alkynyl, provided that R2 and R3 may form an optionally substituted, nitrogenous, saturated, heterocyclic group in cooperation with the adjacent nitrogen) and a medicinal composition containing the compound. The compound functions to inhibit the production of a tumor necrosis factor (TNF-.alpha.) and has satisfactory oral absorbability.
申请公布号 CA2512280(A1) 申请公布日期 2004.09.16
申请号 CA20042512280 申请日期 2004.03.03
申请人 KOWA CO., LTD. 发明人 KUMAI, NATSUYO;YASUOKA, KYOKO;SATO, SEIICHI;MIZOGUCHI, TOSHIMI;KOSHI, TOMOYUKI;TOTSUKA, JUNKO;OHKUCHI, MASAO;TAMURA, MASAHIRO
分类号 A61P1/04;A61P19/02;A61P29/00;A61P37/02;A61P37/08;A61P43/00;C07D405/04;(IPC1-7):C07D405/04;A61K31/501 主分类号 A61P1/04
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