发明名称 |
PROCESS FOR PREPARATION OF INCLUSION COMPOUNDS BETWEEN A NON-STEROIDAL ANTI-INFLAMMATORY DRUG AND BETACYCLODEXTRIN BY MICROWAVE TREATMENT |
摘要 |
<p>A process for the preparation of inclusion complexes of a drug (piroxicam or ibuprofen) and a cyclodextrin, characterised in that: a) the drug and cyclodextrin, in the form of finely divided powders, are mixed in the presence of aqueous or hydroalcoholic solutions, ammonia solutions or acid solutions; b) the resulting mixture is treated in a microwave oven; c) the resulting product is dried under vacuum at room temperature or with heating.</p> |
申请公布号 |
EP1455838(A1) |
申请公布日期 |
2004.09.15 |
申请号 |
EP20020805328 |
申请日期 |
2002.12.17 |
申请人 |
CHIESI FARMACEUTICI S.P.A. |
发明人 |
GIORDANO, FERDINANDO;BETTINI, RUGGERO |
分类号 |
A61K47/48;(IPC1-7):A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|