发明名称 |
Mutant Actinosynnema pretiosum strain with increased maytansinoid production |
摘要 |
A microorganism that is a mutant bacterial strain of the species Actinosynnema pretiosum, designated PF4-4, (ATCC PTA-3921), being capable of producing maytansinoid ansamitocins such as ansamitocin P-3 in improved yield compared to previous known strains, and capable of growth under varied culture conditions, and methods of producing maytansinoid ansamitocins by culturing PF4-4 in a suitable growth medium.
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申请公布号 |
US6790954(B2) |
申请公布日期 |
2004.09.14 |
申请号 |
US20020057561 |
申请日期 |
2002.01.29 |
申请人 |
IMMUNOGEN, INC.;GENENTECH, INC. |
发明人 |
CHUNG JOHNSON;BYNG GRAHAM S. |
分类号 |
C12P17/14;C12N1/20;C12P17/18;(IPC1-7):C07D498/16;C07D498/18 |
主分类号 |
C12P17/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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