发明名称 Mutant Actinosynnema pretiosum strain with increased maytansinoid production
摘要 A microorganism that is a mutant bacterial strain of the species Actinosynnema pretiosum, designated PF4-4, (ATCC PTA-3921), being capable of producing maytansinoid ansamitocins such as ansamitocin P-3 in improved yield compared to previous known strains, and capable of growth under varied culture conditions, and methods of producing maytansinoid ansamitocins by culturing PF4-4 in a suitable growth medium.
申请公布号 US6790954(B2) 申请公布日期 2004.09.14
申请号 US20020057561 申请日期 2002.01.29
申请人 IMMUNOGEN, INC.;GENENTECH, INC. 发明人 CHUNG JOHNSON;BYNG GRAHAM S.
分类号 C12P17/14;C12N1/20;C12P17/18;(IPC1-7):C07D498/16;C07D498/18 主分类号 C12P17/14
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