发明名称 |
SPIRO-SUBSTITUTED PYRROLOPYRIMIDINES |
摘要 |
<p>The invention provides compounds of formula (I) or a pharmaceutically acceptable salt or ester thereof formula (I) wherein the symbols have the meaning as defined in the description. Said compounds are inhibitors of cathepsin K and/or cathepsin S and are useful for the treatment of diseases and medical conditions in which cathepsin K and/or cathepsin S is implicated, e.g. various disorders including neuropathic pain, inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis, multiple sclerosis and tumours.</p> |
申请公布号 |
WO2004076455(A1) |
申请公布日期 |
2004.09.10 |
申请号 |
WO2004EP01982 |
申请日期 |
2004.02.27 |
申请人 |
NOVARTIS AG;NOVARTIS PHARMA GMBH;IRIE, OSAMU;IWASAKI, GENJI;MASUYA, KEIICHI;MIYAKE, TAKAHIRO;TENO, NAOKI |
发明人 |
IRIE, OSAMU;IWASAKI, GENJI;MASUYA, KEIICHI;MIYAKE, TAKAHIRO;TENO, NAOKI |
分类号 |
A61P29/00;C07D519/00;(IPC1-7):C07D487/04;A61K31/00 |
主分类号 |
A61P29/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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