发明名称 |
STATISTICALLY IDENTIFYING AN INCREASED RISK FOR DISEASE |
摘要 |
Methods and computer readable media for statistically identifying an increased risk for disease. In one embodiment, resampling techniques are utilized to consider different genotype combinations within a resampling subset of a case/control data set. Odds-ratios and theoretical p-values are calculated for each genotype combination so that an increased risk of disease associated with a particular genotype combination may be identified. In another embodiment, different genotype combinations within a case/control data set aer considered. Odds ratios are calculated for each genotype combination. Empirical p-values are calculated for the odds ratios through randomization techniques. Using the odds-ratios and/or empirical p-values, an increased risk for disease associated with a particular genotype combination may be identified. |
申请公布号 |
WO2004075010(A2) |
申请公布日期 |
2004.09.02 |
申请号 |
WO2004US04377 |
申请日期 |
2004.02.13 |
申请人 |
INTERGENETICS INCORPORATED;OKLAHOMA MEDICAL RESEARCH FOUNDATION;RALPH, DAVID;ASTON, CHRISTOPHER |
发明人 |
RALPH, DAVID;ASTON, CHRISTOPHER |
分类号 |
G01N33/48;G06F;G06F19/18;G06F19/24 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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