| 摘要 |
<p>A process for producing a polymorph of olanzapine is disclosed, wherein the process comprises: dissolving an initial polymorph of olanzapine in aqueous acidic solution; wherein the aqueous acidic solution comprises an acid selected from the group consisting of organic and inorganic acids; and precipitating a different polymorph of olanzapine by neutralisation; wherein neutralisation is accomplished by the addition of an aqueous or alcoholic solution of a base.</p> |
