| 摘要 |
A compound of formula I wherein: X represents a bond or a group selected from substituted or unsubstituted alkyl, NH-C(O)-alkyl, NH-C(O)-CH2-O-CH2 or C(O)-NH-(amino acid residue); Y represents NR4, O or S; R1 represents H, halo, CF3, lower alkyl or lower alkoxy; R2 and R4 represents independently H or lower alkyl; and R3 represents H, halo, lower alkyl or lower alkoxy; Wherein halo represents F, Cl or Br; lower alkyl represents saturated or unsaturated, straight, branched or cyclic alkyl froups having 1-6 carbon atoms; and lower alkoxy represents saturated or unsaturated, straight, branched or cyclic alkoxy groups having 1-6 carbon atoms, with the proviso that R2 is not H, when X is a bond, Y is NH and R3 is H. Also disclosed is a pharmaceutical composition comprising said compound, for the treatment of medical conditions from the group of: rheumatoid arthritis, multiple sclerosis, diabetes, asthma, transplantation, systemic lupus, eruthematosis and psoriasis.
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