| 发明名称 |
Tyrosine derivatives as phosphatase inhibitors |
| 摘要 |
Disclosed are compounds of the formula (I), and pharmaceutically acceptable salts and prodrugs thereof, wherein A, B, R1, R2, R3, R4 and R5 are as defined in the specification. Such compounds are tyrosine phosphatase inhibitors and useful in the treatment or prevention of Type II Diabetes Mellitus. Also disclosed are formulations comprising these compounds, processes for preparing such compounds and a method for treating or preventing Type II Diabetes Mellitus.
|
| 申请公布号 |
NZ523483(A) |
申请公布日期 |
2004.08.27 |
| 申请号 |
NZ20010523483 |
申请日期 |
2001.07.05 |
| 申请人 |
ARRAY BIOPHARMA INC |
发明人 |
BURGESS, LAURENCE E;GAUDINO, JOHN;GRONEBERG, ROBERT D;NORMAN, MARK H;RODRIGUEZ, MARTHA E;SUN, XICHENG;WALLACE, ELI M |
| 分类号 |
A61K31/192;A61K31/194;A61K31/196;A61K31/341;A61K31/4045;A61K31/41;A61K31/4402;A61P3/10;A61P7/12;A61P35/00;A61P43/00;C07C237/22;C07C311/13;C07C311/19;C07C311/29;C07D209/14;C07D209/16;C07D213/40;C07D257/04;C07D307/52;(IPC1-7):C07C311/19;A61K31/165;A61K31/166 |
主分类号 |
A61K31/192 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
