METHODS FOR IDENTIFYING RISK OF MELANOMA AND TREATMENTS THEREOF

摘要

Provided herein are methods for identifying risk of melanoma in a subject and/or subjects at risk of melanoma, reagents and kits for carrying out the methods, methods for identifying candidate therapeutics for treating melanoma, therapeutic methods for treating melanoma in a subject and compositions comprising one or more melanoma cells and one or more NRPl, NID2 or END0180 directed agents. These embodiments are based upon an analysis of polymorphic variations in a NRPl, NID2 or END0180 nucleic acid, exemplified by nucleotide sequences of SEQ ID NO: 1, 2 or 3.