发明名称 Method for the synthesis of peptide salts, their use and the pharmaceutical preparations, containing peptide salts
摘要 A method for producing peptide salts, including reacting an acid addition salt of a basic starting peptide in the presence of a diluent in a mixed bed ion exchanger, with a mixture of an acid and a basic ion exchanger during the formation of a free basic peptide, and then separating the ion exchanger and then the free basic peptide, with an inorganic or organic acid, and then forming the desired acid addition salt of the peptide, and removing the diluent.
申请公布号 US6780972(B2) 申请公布日期 2004.08.24
申请号 US20010939532 申请日期 2001.08.24
申请人 ZENTARIS GMBH 发明人 DAMM MICHAEL;SALONEK WALDEMAR;ENGEL JUERGEN;BAUER HORST;STACH GABRIELE
分类号 A61K38/00;A61K;A61K38/09;A61P;A61P5/02;A61P5/04;A61P13/08;A61P15/00;A61P35/00;C07K;C07K1/00;C07K1/107;C07K1/113;C07K7/23;C07K14/575;(IPC1-7):C07K1/00;C07K1/18 主分类号 A61K38/00
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