| 摘要 |
In order to provide a molded product capable of manifesting a desired release control pattern of an effective ingredient by direct tabletting method, a controlled release molded product was devised characterized in having an outer layer and a plurality of cores or a core partially provided with constrictions and portions that can be substantially identified as a plurality of cores and controlling release of the effective ingredient contained in the core portion according to the distance from the outside of the molded product to individual core. The molded product of the present invention can also be used in a dividable controlled release molded product in which the release property remains unchanged after division by providing a structure coupling a plurality of unit molded products and ensuring that the distance from the division surface to the core is sufficiently longer than the distance from the external reference plane on the molded product surface that stipulates the distance from the outside of the molded product to the core. It is possible to readily manufacture the molded product of the present invention using integral compression molding means having a double-structured punch - punch consisting of a core punch and an outer punch enclosing part or whole of the outer perimeter of the core punch - above and below a die. <IMAGE>
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