发明名称 Sugar-modified liposome and products comprising the liposome
摘要 The present invention provides a sugar-modified liposome having a sugar chain bonded to its membrane surface, preferably through a linker protein, and having excellent absorption qualities, particularly in the intestine. The molecular structure and quantity of the sugar chain is selectively varied to allow the liposome to be delivered in a targeted manner to selected cells and tissues. The liposome is applicable to medicinal drugs, cosmetics and other various products in the medical/pharmaceutical fields, and it is especially useful in a therapeutic drug delivery system that recognizes target cells and tissues, such as cancer cells, and in the delivery of drugs or genes locally to a selected region, or in a diagnostic cell/tissue sensing probe.
申请公布号 EP1447081(A1) 申请公布日期 2004.08.18
申请号 EP20030250952 申请日期 2003.02.17
申请人 NATIONAL INSTITUE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY 发明人 YAMAZAKI, NOBORU.;KOJIMA, SHUJI.
分类号 A61K9/127;A61K47/48;(IPC1-7):A61K9/127 主分类号 A61K9/127
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