| 摘要 |
Compounds of formula I in the form of their racemates or enantiomers,preferably compounds of formula IawhereinR4 is C1-C6alkyl, Z is chlorine, bromine or iodine, and X is -OH, chloride, bromide or iodide, or X forms an ester group with the carbonyl substituent, as well as salts of carboxylic acids. The compounds are valuable intermediates for the propagation of delta-amino-gamma-hydroxy-omega-aryl-alkanecarboxamides, which exhibit renin-inhibiting properties and could be used as antihypertensive agents in pharmaceutical preparations.
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