发明名称 |
Soft shell gelatin capsules containing non-steroidal anti-inflammatories |
摘要 |
The present invention provides a pharmaceutical formulation suitable for filling softgel capsules comprising: (a) a therapeutically effective amount of a non-steroidal anti-inflammatory drug selected from the group consisting of selected from the group consisting of (1) the propionic acid derivatives; (2) the acetic acid derivatives; (3) the fenamic acid derivatives; (4) the biphenylcarboxylic acid derivatives; and (5) the oxicams; as well as Cox 2 inhibitors and mixtures thereof; and (b) a solvent system comprising 40% to 60% by weight a polyoxyethylene ether of the formula: wherein n=1 to 6; 15% to 35% by weight of glycerin and 15% to 35% by weight water. In the case of compositions containing an NSAID having carboxyl function an alkaline hydroxide may be added to neutralize said hydroxide function.
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申请公布号 |
US2004156892(A1) |
申请公布日期 |
2004.08.12 |
申请号 |
US20040773256 |
申请日期 |
2004.02.09 |
申请人 |
PROCAPS SA |
发明人 |
BERTHEL ALFREDO;GOMEZ JORGE |
分类号 |
A61K9/64;A61K31/192;(IPC1-7):A61K9/48 |
主分类号 |
A61K9/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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