发明名称 |
Solid phase synthesis of LXR ligands |
摘要 |
The invention provides solid support synthetic methods for producing combinatorial libraries of modulators of LXRs. The combinatorial libraries thus produced are useful both as diagnostic indicators of LXRalpha function and as pharmacologically active agents. The combinatorial libraries find particular use in the treatment of disease states associated with cholesterol metabolism, particularly atherosclerosis and hypercholesterolemia.
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申请公布号 |
US2004152132(A1) |
申请公布日期 |
2004.08.05 |
申请号 |
US20030749530 |
申请日期 |
2003.12.30 |
申请人 |
TULARIK INC.;SUMITOMO PHARMACEUTICALS CO., LTD. |
发明人 |
MEDINA JULIO;IMAZAKI NAONORI |
分类号 |
A61P9/10;C07B61/00;C07C231/02;(IPC1-7):G01N33/53;C07C251/16 |
主分类号 |
A61P9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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