| 摘要 |
A compound having a binding affinity for both the alpha-v-beta-3 receptor and a neuro-peptide receptor, and an improved overall affinity for tumours, which comprises a first peptide part comprising at least one occurrence of the amino acid sequence Arg-Gly-Asp, and a second peptide part coupled thereto, optionally via a linker, said second part being a neuro-peptide selected from the group consisting of cholecystokinin (CCK), gastrin, substance P, bombesine, vasoactive intestinal peptide (VIP), pituitary adenylate cyclase activating peptide (PACAP), somatostatin and analogues thereof.
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