A method of detecting increased levels of DNA single strand breaks in a eukaryotic cell sample, comprising the steps of: (a) contacting a eukaryotic cell sample to a water-soluble tetrazolium salt under conditions in which said tetrazolium salt is converted to a formazan dye in said cell sample in the presence of NADH or NADPH; and then (b) detecting the presence of the formazan dye in said cell sample, with decreased levels of the formazan dye indicating increased levels of DNA single strand breaks in the eukaryotic cell sample.
申请公布号
WO2004063353(A2)
申请公布日期
2004.07.29
申请号
WO2004US00068
申请日期
2004.01.06
申请人
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;NAKAMURA, JUN;SWENBERG, JAMES, A.