N- (1-BENZYL-2-OXO-2- (1-PIPERAZINYL) ETHYL) -1-PIPERIDINCARBOXAMID-DERIVATIVES AND RELATED COMPOUNDS USE AS CGRP-ANTAGONISTS FOR TREATING A HEADACHE

摘要

The invention relates to carboxylic acids and esters of a general formula (I ), wherein Ar, R, R1, X1, X3, X4, Y and Y1 have a definition given in a claim 1 . Said invention also relates to tautomers, the enantiomers, mixtures and salt s thereof, in particular to physiologically compatible salts containing organi c or inorganic acids or bases, drugs containing said compounds using them as CGRT antagonists for treating a headache and to method for the production an d use thereof for producing and cleaning antibodies and as labelled compounds for RIA and ELISA biological dosages and, finally as auxiliary diagnostics o r analytics for neutrotransmitters.