发明名称 CULTURAL INACTIVATED VACCINE AGAINST CHLAMYDIOSIS IN CATTLE AND SHEEP AND GOATS
摘要 FIELD: veterinary microbiology, virology, agriculture. ^ SUBSTANCE: invention relates to the development of specific, highly immunogenic vaccine against chlamydiosis in cattle and sheep and goats and exhibiting low reactivity. Vaccine comprises phenol, the strain Chlamydia psittaci (var. bovis) VGNKI "B-75" 18 as an antigen cultured in chicken embryo fibroblast cell primary monolayer culture with titer 10-7.0 TCD 50/ml, not less; polyvinylpyrrolidone as an adjuvant in the ratio, wt.-%: Chlamydia psittaci (var. bovis) VGNKI "B-75" 18 with titer 10-7 TCD 50/ml, 99.0-99.5; phenol, 0.3-0.5; polyvinylpyrrolidone, 0.4-0.6. Vaccine shows high immunogenic properties and low reactivity. ^ EFFECT: valuable properties of vaccine. ^ 10 tbl
申请公布号 RU2233174(C2) 申请公布日期 2004.07.27
申请号 RU20020107140 申请日期 2002.03.21
申请人 发明人 SHCHERBAN' G.P.;DANCHENKO G.N.;KRAVCHENKO T.F.
分类号 A61K39/118;C12N1/20 主分类号 A61K39/118
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