| 发明名称 |
Methods and compositions for stabilizing microtubules and intermediate filaments in striated muscle cells |
| 摘要 |
The present invention discloses new muscle ring finger (MURF) proteins designate MURF-1, MURF-2 and MURF-3. The genes encoding these MURFs also are provided. MURFs interact with microtubules and thus play a role in cytoskeletal function, mitosis and cell growth. Thus, the uses of MURFs in diagnosis, treatment and drug screening, in particular relation to cardiomyopathies, are described.
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| 申请公布号 |
US2004142446(A1) |
申请公布日期 |
2004.07.22 |
| 申请号 |
US20040775627 |
申请日期 |
2004.02.10 |
| 申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
OLSON ERIC N.;SPENCER JEFFREY A. |
| 分类号 |
A61K38/00;C07K14/47;C12N15/12;(IPC1-7):C12N9/64;C07H21/04 |
主分类号 |
A61K38/00 |
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