发明名称 |
Modified luciferase nucleic acids and methods of use |
摘要 |
The luxA and luxB genes from P. luminescens which encode for the luciferase protein of the bacterial luciferase system were modified to generate codon-optimized versions that are optimized for expression in mammalian cells. The codon-optimized bacterial luciferase enzyme system genes of the invention can be used to develop a mammalian bioluminescence bioreporter useful in various medical research and diagnostics applications.
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申请公布号 |
US2004142356(A1) |
申请公布日期 |
2004.07.22 |
申请号 |
US20030697419 |
申请日期 |
2003.10.30 |
申请人 |
PATTERSON STACEY;GUPTA RAKESH;SAYLER GARY;DIONISI HEBE |
发明人 |
PATTERSON STACEY;GUPTA RAKESH;SAYLER GARY;DIONISI HEBE |
分类号 |
C12N1/21;C12N5/22;C12N9/02;(IPC1-7):C12Q1/68;C12Q1/66;C07H21/04;C12N9/06 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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