发明名称 PEPTIDES INHIBITING GROWTH TRANSFORMING FACTOR TGF-BETA-1
摘要 FIELD: peptides, medicine, pharmacy. ^ SUBSTANCE: invention relates to synthetic peptides as antagonists in binding the growth transforming factor TGF-beta1 with its receptors in body being this factor shows the sequence comprising from 2 to 15 amino acids that are identical or related with amino acids in the natural the growth transforming factor TGF-beta1 and/or its receptors. Peptides can be used as active compounds for preparing compositions used in liver diseases, in particular, in liver fibrosis (cirrhosis). ^ EFFECT: valuable medicinal properties of peptides. ^ 10 cl, 7 tbl, 28 dwg
申请公布号 RU2232771(C2) 申请公布日期 2004.07.20
申请号 RU20010117230 申请日期 1999.11.23
申请人 发明人 EHSKERRO SAEHNS IGNASIO KHOSE;LASARTE SAGASTIBELSA KHUAN KHOSE;PR'ETO VALTUEHN'JA KHESUS;BORRAS KUEHSTA FRANSISKO
分类号 A61K45/00;A61K38/00;A61K48/00;A61P1/16;A61P43/00;C07K14/495;C07K14/71 主分类号 A61K45/00
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