发明名称 |
Anti-cancer 2,3-dihydro-1h-pyrrolo[3,2-f[quinoline complexes of cobalt and chromium |
摘要 |
This invention relates to a class of heterocycles and their metal complexes, and is particularly concerned with the use of these compounds in the preparation of prodrugs or as prodrugs that may be activated under hypoxic conditions by enzymes or by therapeutic ionising radiation, in the treatment of cancer. The invention also relates to the use of these heterocycles and the corresponding metal complexes in the preparation of medicaments and to compositions including the heterocycles or their metal complexes and to methods for preparing these compounds.
|
申请公布号 |
US2004138195(A1) |
申请公布日期 |
2004.07.15 |
申请号 |
US20040470155 |
申请日期 |
2004.01.29 |
申请人 |
DENNY WILLIAM ALEXANDER;WILSON WILLIAM ROBERT;WARE DAVID CHARLES;ATWELL GRAHAM JOHN;MILBANK JARED BRUCE;STEVENSON RALPH JAMES |
发明人 |
DENNY WILLIAM ALEXANDER;WILSON WILLIAM ROBERT;WARE DAVID CHARLES;ATWELL GRAHAM JOHN;MILBANK JARED BRUCE;STEVENSON RALPH JAMES |
分类号 |
C07D215/30;A61K31/404;A61K31/437;A61K31/47;A61P35/00;A61P43/00;C07D209/60;C07D255/02;C07D257/00;C07D257/02;C07D471/04;C07F11/00;C07F15/06;(IPC1-7):A61K31/555 |
主分类号 |
C07D215/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|