摘要 |
This invention relates to hydrolase fluorogenic substrates with improved cell permeability, methods for the preparation thereof, and methods of measuring activities of hydrolases, particularly in cell-based assays. The substrates easily diffuse into the cells, where they are enzymatically processed to yield photostable fluorescent products, and are particularly fitted for visualising enzyme-derived activities in cell-based assays. |
申请人 |
TIBOTEC BVBA;GOEMAN, JAN, LUDWIG;VAN ACKER, KOENRAAD, LODEWIJK, AUGUST;VAN DER EYCKEN, JOHAN, THEO, ANDRE;DIERYNCK, INGE |
发明人 |
GOEMAN, JAN, LUDWIG;VAN ACKER, KOENRAAD, LODEWIJK, AUGUST;VAN DER EYCKEN, JOHAN, THEO, ANDRE;DIERYNCK, INGE |