| 发明名称 |
Process for the preparation of an essentially pure polymorph of an n-pyrazolyl-n'-naphthyl-urea |
| 摘要 |
Disclosed are improved processes for the preparation of a polymorph of 1-[tert-butyl-1-p-tolyl-1H-pyrazol-5-yl]-3-[4-(2-morpolinin-4-yl-ethoxy)naphthalen-1-yl]-urea (1) by crystallization from an alcohol, wherein the improvement is that crude (1) is treated with ethanol.
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| 申请公布号 |
US2004138216(A1) |
申请公布日期 |
2004.07.15 |
| 申请号 |
US20030727214 |
申请日期 |
2003.12.03 |
| 申请人 |
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG |
发明人 |
SAMSTAG WENDELIN;KOCH GUNTER |
| 分类号 |
A61P37/00;C07D231/40;(IPC1-7):A61K31/537;C07D413/02 |
主分类号 |
A61P37/00 |
| 代理机构 |
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