发明名称 SUBSTITUTED DERIVATIVES OF IMIDAZOLE, METHOD FOR ADMINISTRATION OF PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATMENT BASED ON THESE COMPOUNDS
摘要 FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to derivatives of imidazole of the formula (1) ^ ^ wherein X, Y, R, R2, R3 and R4 are given in the invention claim. These compounds are selective agonists with respect to adrenoceptors of subtype(s) alpha2B or alpha2B/alpha2C. Also, invention describes a method for administration of pharmaceutical composition and method for treatment based on these compounds. ^ EFFECT: improved administration and treatment methods, valuable properties of compounds. ^ 86 cl, 6 tbl, 67 ex
申请公布号 RU2232154(C2) 申请公布日期 2004.07.10
申请号 RU20010107028 申请日期 2000.06.08
申请人 发明人 CHAU KEN;DZHIL DANIEL U.;BERK DZHEJMS A.;KHARKORT DEJL A.;GARST MAJKL I.;UILER LARRI A.;MANK STIVEN A.
分类号 A61K31/4164;A61K31/421;A61K31/538;A61P27/06;A61P43/00;C07D233/04;C07D233/10;C07D233/54;C07D233/84;C07D263/28;C07D401/06;C07D403/06;C07D405/06;C07D409/06;C07D413/12;C07D495/04 主分类号 A61K31/4164
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