摘要 |
FIELD: organic chemistry, medicine, pharmacy. ^ SUBSTANCE: invention relates to derivatives of imidazole of the formula (1) ^ ^ wherein X, Y, R, R2, R3 and R4 are given in the invention claim. These compounds are selective agonists with respect to adrenoceptors of subtype(s) alpha2B or alpha2B/alpha2C. Also, invention describes a method for administration of pharmaceutical composition and method for treatment based on these compounds. ^ EFFECT: improved administration and treatment methods, valuable properties of compounds. ^ 86 cl, 6 tbl, 67 ex |