发明名称 TACIS AND BR3 POLYPEPTIDES AND USES THEREOF.
摘要 <p>Novel receptors, referred to herein as "TACIs" and "BR3", agonists and antagonists thereof, and methods of using TACIs and BR3, as well as agonists or antagonists thereof, to modulate for example, activity of tumor necrosis factor (TNF) and TNFR-related molecules, including members of the TNF and TNFR families referred to as TALL-1, APRIL, TACI, and BCMA, are provided. Methods for in vitro, in situ, and/or in vivo diagnosis and/or treatment of mammalian cells or pathological conditions associated with such TNF and TNFR-related molecules are further provided.</p>
申请公布号 MXPA04001050(A) 申请公布日期 2004.07.08
申请号 MX2004PA01050 申请日期 2002.07.24
申请人 GENENTECH, INC. 发明人 VISHVA DIXIT
分类号 G01N33/50;A61K38/00;A61K39/395;A61P1/02;A61P1/04;A61P3/10;A61P5/14;A61P7/06;A61P9/00;A61P9/12;A61P11/00;A61P11/06;A61P13/00;A61P13/12;A61P17/00;A61P19/02;A61P19/08;A61P21/04;A61P27/02;A61P29/00;A61P31/04;A61P31/10;A61P31/20;A61P35/00;A61P37/02;A61P43/00;C07K14/715;C07K16/28;C07K19/00;C12N;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12P21/08;C12Q1/02;G01N33/15;(IPC1-7):C12N 主分类号 G01N33/50
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