发明名称 |
COMPLEXES OF E-2-METHOXY-N-(3-{4-[3-METHYL-4-(6-METHYL-PYRIDIN-3-YLOXY)-PHENYLAMINO]-QUINAZOLIN-6-YL}-ALLYL)-ACETAMIDE, THEIR METHOD OF PRODUCTION, AND USE |
摘要 |
The invention relates to complexes of E-2-Methoxy-N-(3-{4-[3-methyl-4-(6- methyl~pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide havin g the following formula I: The invention also relates to pharmaceutical compositions containing the complexes of formula I. The invention further relates to methods of treating hyperproliferative diseases, such as cancers, in mammals, especially humans by administering the above complexes and to methods of preparing the above complexes.
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申请公布号 |
CA2509140(A1) |
申请公布日期 |
2004.07.08 |
申请号 |
CA20032509140 |
申请日期 |
2003.12.08 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
KATH, JOHN CHARLES;RICHTER, DANIEL TYLER;THOMPSON, CARL BRIAN;MORRIS, JOEL;LI, ZHENG JANE;TRASK, ANDREW VINCENT;LEONARD, JASON ALBERT |
分类号 |
A61K31/517;C07D401/12;(IPC1-7):C07D401/12;A61K31/505 |
主分类号 |
A61K31/517 |
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