发明名称 |
OPTICALLY ACTIVE AZIRIDINE-2-CARBOXYLATE DERIVATIVES AND A PROCESS FOR PREPARING THEM |
摘要 |
This invention relates to compounds of Formula I having an aziridine-2-carboxylic group and a menthol group, a process for preparing such compounds, a method for obtaining optically active aziridine-2-carboxylate derivatives by optical resolution of such compounds, and optically active aziridine-2-carboxylate derivatives obtained by the same method: wherein R<SUP>1 </SUP>is hydrogen; alkyl; cycloalkyl; 4-chlorophenyl; 4-methoxyphenyl; s-triazinyl or pyridinyl acyl; benzyl; hydrocarbon residue which may be substituted with a substituent selected from the group consisting of hydroxy, alkoxy, dialkylamino, phenyl, 4-chlorophenyl and 4-methoxyphenyl; 2,4-dimethoxyphenyl; substituted phenyl including (1R)-phenylethyl or (1S)-phenylethyl. Preferences are given to (1R)-phenylethyl and (1S)-phenylethyl. Menthol is selected from the group consisting of (+)-menthol and (-)-menthol. |
申请公布号 |
EP1309550(A4) |
申请公布日期 |
2004.07.07 |
申请号 |
EP20010957024 |
申请日期 |
2001.08.10 |
申请人 |
CHEMBIONEX CO., LTD;HANSOL CHEMIENCE CO., LTD. |
发明人 |
LEE, WON, KOO;PARK, CHAN, SUN;LIM, YEON, HWA;HA, HYUN-JOON |
分类号 |
C07D203/06;C07D203/08;C07D203/18 |
主分类号 |
C07D203/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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