发明名称 |
STABLE POLYMORPH OF N-(3-ETHYNYLPHENYLAMINO)-6,7-BIS(2-METHOXYETHOXY)-4-QUI-NAZOLINAMINE HYDROCHLORIDE, METHODS OF PRODUCTION, AND PHARMACEUTICAL USES THEREOF |
摘要 |
The present invention relates to crystalline forms of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride, their production in essentially pure form, and their use. The invention also relates to the pharmaceutical compositions containing the crystalline forms of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine as hydrochloride and to methods of treating hyperproliferative disorders, such as cancer, by administering the compound. |
申请公布号 |
HRP20020388(A2) |
申请公布日期 |
2004.06.30 |
申请号 |
HR2002P000388 |
申请日期 |
2002.05.03 |
申请人 |
OSI PHARMACEUTICALS |
发明人 |
RICHARD;JAMES;MICHAEL;SHAMA MOHAMMED KAJIJI;BARBARA;KAREN;TYMOTHY NORRIS;JEFFREY W. RAGGON;SANDRA |
分类号 |
A61K9/20;A61K31/505;A61K31/517;A61K38/45;A61K38/46;A61K38/55;A61K39/395;A61K45/00;A61K45/06;A61P9/10;A61P35/00;A61P37/02;A61P43/00;B01D9/02;C07D239/04;C07D239/94 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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