发明名称 |
Linoleic acid diol and glucuronide conjugate levels as diagnostic markers of disorders of abnormal regulation of cytochrome P450 metabolism of unsaturated fatty acids |
摘要 |
The invention provides methods of using dihydroxy unsaturated fatty acids as markers for identifying patients with a disorder associated with abnormal regulation of the cytochrome P450 metabolism or oxidation of unsaturated fatty acids. For example, linoleic acid diols, including leukotoxindiol, can be used as a diagnostic tool for identifying patients with pre-eclampsia, eclampsia, and pregnancy-induced hypertension.
|
申请公布号 |
US6756210(B2) |
申请公布日期 |
2004.06.29 |
申请号 |
US20010867963 |
申请日期 |
2001.05.29 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
HAMMOCK BRUCE;ZUREK GABRIELA;GEE SHIRLEY;NEWMAN JOHN W.;ZHENG JIANG |
分类号 |
A61K49/00;C12Q1/26;G01N33/92;(IPC1-7):C12Q1/26 |
主分类号 |
A61K49/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|