<p>Compounds, compositions and methods are provided for modulating the expression of Interleukin 18. The compositions comprise oligonucleotides, targeted to nucleic acid encoding Interleukin 18. Methods of using these compounds for modulation of Interleukin 18 expression and for diagnosis and treatment of disease associated with expression of Interleukin 18 are provided.</p>
申请公布号
WO2004053169(A1)
申请公布日期
2004.06.24
申请号
WO2003US39507
申请日期
2003.12.11
申请人
ISIS PHARMACEUTICALS INC.;BAKER, BRENDA, F.;DOBIE, KENNETH, W.