Method of confirming the presence of myocardial infarction

摘要

The mass distribution and intensity of polypeptides from human sera obtained using mass spectrometry has served as a fingerprint used to diagnose disease. The instant invention relates to a method for diagnosing and distinguishing a myocardial infarction in a particular human subject by comparing a serum protein profile of the particular human subject to the reference serum protein profiles of at least two or more defined subsets of human subjects wherein said serum protein profiles are generated by mass spectrometry comprising the steps of; identifying areas of the serum protein profiles that are different in signal intensity; reducing the dimensionality of the areas identified; elucidating a metric, and analyzing the data elucidated in order to diagnose and distinguish a myocardial infarction in a particular human subject.