METHOD FOR PRODUCTION AND A COMPOSITION FOR IMMOBILISING BIOLOGICAL MACROMOLECULES IN HYDROGELS AND THE USE OF SAID COMPOSITION FOR PRODUCING BIOCHIPS

摘要

The present invention refers to the field of molecular biology and bio-organic chemistry and deals with compositions for immobilization of modified oligonucleotides, proteins, nucleic acids or any other molecules bearing the unsaturated groups in a hydrogel, in manufacturing microchips by method of photo-initiated copolymerization. The invention also refers to the technology for manufacturing microchips and to performing a polymerase chain reaction (PCR) over a chip having an application in molecular biology for sequencing and mapping of DNA, detection of mutations, and in a whole lot of medical applications.