发明名称 ANTISENSE MODULATION OF CHOLESTERYL ESTER TRANSFER PROTEIN EXPRESSION
摘要 <p>Antisense compounds, compositions and methods are provided for modulating the expression of cholesteryl ester transfer protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding cholesteryl ester transfer protein. Methods of using these compounds for modulation of cholesteryl ester transfer protein expression and for treatment of diseases associated with expression of cholesteryl ester transfer protein are provided.</p>
申请公布号 EP1430072(A2) 申请公布日期 2004.06.23
申请号 EP20020794669 申请日期 2002.08.05
申请人 ISIS PHARMACEUTICALS, INC. 发明人 CROOKE, ROSANNE, M.;GRAHAM, MARK, J.;NERO, PAMELA, S.;WANCEWICZ, EDWARD
分类号 A61K38/00;A61K48/00;C07H21/02;C12N15/113;(IPC1-7):C07H21/04;C12Q1/68;C12N15/11 主分类号 A61K38/00
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