发明名称 LABELLED COMPOUND
摘要 The present Invention provides a labelled .beta.-cyano-L-alanine and a .gamma.-cyano-.alpha.-aminobutyric acid, of which cyano group carbon is labelled with radionuclids 11C or 14C, or stable isotope 13C. The present invention also provides a labelled amino acids such as asparagine, asparatic acid, DABA, GABA, glutamine and glutamic acid synthesized by using the labelled .beta.-cyano-L-alanine and the .gamma.-cyano-.alpha.-aminobutyric acid as an intermediate. The labelled amino acids are useful for in vivo imaging of tumors and bra in functions.
申请公布号 CA2172455(C) 申请公布日期 2004.06.22
申请号 CA19962172455 申请日期 1996.03.22
申请人 FURUYA, YUJI;RESEARCH DEVELOPMENT CORPORATION OF JAPAN;OMURA, HIRONORI 发明人 WATANABE, YASUYOSHI;FURUYA, YUJI;ANTONI, GUNNAR;OMURA, HIRONORI;LANGSTROM, BENGT
分类号 A61K51/04;(IPC1-7):C12P13/04;C07B59/00;C07C229/24;C07C229/26;C07C237/06;C07C255/28;C07K2/00 主分类号 A61K51/04
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