发明名称 |
COMPOSITION COMPRISING A TRAMADOL MATERIAL AND ACETAMINOPHENAND ITS USE |
摘要 |
This invention relates to a composition comprising a tramadol material and acetaminophen, and its use. As used herein tramadol refers to various forms of tramadol. The compositions are pharmacologically useful in treating pain and tussive conditions. The compositions are also subject to less opioid side-effects su ch as abuse liability, tolerance, constipation and respiratory depression. Furthermore, where the components of the compositions are within certain ratios the pharmacological effects of the compositions are superadditive (Synergistic).
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申请公布号 |
CA2095523(C) |
申请公布日期 |
2004.06.22 |
申请号 |
CA19922095523 |
申请日期 |
1992.09.03 |
申请人 |
MCNEILAB, INC. |
发明人 |
RAFFA, ROBERT B.;VAUGHT, JEFFREY L. |
分类号 |
A61K31/135;A61K31/165;A61K31/166;A61K31/167;A61P25/04;A61P29/00;(IPC1-7):A61K31/505 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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