NOVEL ACTIVATED POLYETHYLENE GLYCOL COMPOUNDS

摘要

The present invention involves new polyethylene glycol derivatives that can be reacted with biological materials to covalently attach the polyethylene glycol derivative to the material. The biological materials may include proteins, liposomes, or cellular compositions. The attachment of the polyethylene glycol to the materials results in improved biological properties, such as reduced elimination of the materials by the immune system. In the case of red blood cells, the attachment of the compound provides either antigen masking of the red cells or improved viscosity of the red cells at low shear rates.