| 摘要 |
The present invention provides novel methods and means for the preparation of vaccines that are capable of eliciting strong immune responses, especially through intranasal delivery. The invention discloses particles, referred to as `co-micelles' in which antigens are present that interact through hydrophobic interactions with certain specific types of amphiphilic compounds, wherein said amphiphilic compounds have adjuvant activity and wherein said antigens are preferably antigenic surface proteins, such as integral membrane proteins from infectious agents like viruses. |
