发明名称 |
Antisense modulation of insulin-like growth factor binding protein 5 expression |
摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of insulin-like growth factor binding protein 5. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding insulin-like growth factor binding protein 5. Methods of using these compounds for modulation of insulin-like growth factor binding protein 5 expression and for treatment of diseases associated with expression of insulin-like growth factor binding protein 5 are provided.
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申请公布号 |
US6750019(B2) |
申请公布日期 |
2004.06.15 |
申请号 |
US20010975123 |
申请日期 |
2001.10.09 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
FREIER SUSAN M. |
分类号 |
C12N15/09;A61K31/7088;A61K38/00;A61K48/00;C07H21/04;C12N15/113;C12Q1/68;(IPC1-7):C12Q1/68;C12P19/34;C12N15/88;C07H21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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