COMPOSITION FOR SUPPRESSING SMOOTH MUSCLE PROLIFERATION, AND COMPOSITIONS FOR PREVENTING AND TREATING ARTERIOSCLEROSIS AND RESTENOSIS AFTER REVASCULARIZATION

摘要

PROBLEM TO BE SOLVED: To provide a treating and diagnostic technique using a gene associated with obesity or its expression by elucidating the obesity-related gene and its expression each useful for etiology elucidation and treatment technique of several diseases associated with obesity, especially of arteriosclerosis such as stenocardia and myocardial infarction. SOLUTION: The subject composition for suppressing smooth muscle proliferation, the subject composition for preventing and treating arteriosclerosis and the subject composition for preventing and treating restenosis after revascularization contain each a pharmaceutically effective amount of one selected from adipose tissue specific secretor factor apM1 and pharmaceutically permissible salts thereof together with a pharmaceutically permissible carrier. COPYRIGHT: (C)2004,JPO